Development and validation of RP-HPLC assay of chlorhexidine in gingival crevicular fluid
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Development and validation of RP HPLC method for determination of betamethasone dipropionate in gingival crevicular fluid.
Abstract A simple RP HPLC method for quantification of betamethasone dipropionate (BDP) in gingival crevicular fluid (GCF) has been developed and validated. GCF represents a valuable matrix for therapeutic monitoring of drugs used in the treatment of periodontal disease. The proposed method involves single step extraction for sample preparation. The calibration curve for BDP was linear over the...
متن کاملThe HPLC assay of concentration of azithromycin from two different manufacturers in gingival crevicular fluid (GCF)
Background: Azithromycin (AZM) is used in periodontal infections. The present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the HPLC method. Methods: Two groups (n=15) of healthy volunteers participated in this study. The first group received an imported azithromycin (ImAZM) tablet (250 mg, PO) and the second group received an ...
متن کاملThe HPLC assay of concentration of azithromycin from two different manufacturers in gingival crevicular fluid (GCF)
BACKGROUND Azithromycin (AZM) is used in periodontal infections. The present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the HPLC method. METHODS Two groups (n=15) of healthy volunteers participated in this study. The first group received an imported azithromycin (ImAZM) tablet (250 mg, PO) and the second group received an azi...
متن کاملthe hplc assay of concentration of azithromycin from two different manufacturers in gingival crevicular fluid (gcf)
background: azithromycin (azm) is used in periodontal infections. the present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the hplc method. methods: two groups (n=15) of healthy volunteers participated in this study. the first group received an imported azithromycin (imazm) tablet (250 mg, po) and the second group received an azi...
متن کاملGingival Crevicular Fluid Biomarkers
Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...
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ژورنال
عنوان ژورنال: Arhiv za farmaciju
سال: 2014
ISSN: 0004-1963
DOI: 10.5937/arhfarm1402069b